You cannot truly know with certainty. The question is generally asked because of the situations one goes through in life and the yearning to exit these situations and circumstances one is facing. The decision is made outside of the simulation by your higher Self from the standpoint of love. 

Now I will say that there are clues that might reveal themselves that the end is near like the lessons you learn while you are going through your experiences. What your main focus in life is and how you view existence can give you a hint as to where you are in your evolutionary trajectory. But to know for certainty. No.